Effects of heart rate in modified look-locker inversion recovery (MOLLI) T1 mapping
نویسندگان
چکیده
Background MOLLI is a method of producing a T1 map at end diastole by using the electrocardiogram (ECG) under respiratory arrest to obtain consecutive inversion recovery images with an arbitrary number of MOLLI cycles. Since a variety of heart rates are presumed clinically, it is important to understand their effects on the T1 value and the error of measurement. We investigated the error of measurement in MOLLI T1 mapping caused by changes in the heart rate.
منابع مشابه
A segmented modified look-locker inversion recovery (MOLLI) sequence for high heart rate T1 mapping of mice
Background Quantitative T1 mapping provides myocardial tissue characterization for assessment of various cardiomyopathies. The Modified Look-locker (MOLLI) sequence is widely used for mapping the T1quantification, where multiple single-shot images are acquired along the T1 recovery curve after an inversion pulse. However, single-shot imaging becomes infeasible for mouse imaging at high heart ra...
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T1 mapping is a promising quantitative tool for assessing diffuse cardiomyopathies. The purpose of this study is to quantify in vivo accuracy of the Modified Look-Locker Inversion Recovery (MOLLI) cardiac T1 mapping sequence against the spin echo gold standard, which has not been done previously. T1 accuracy of MOLLI was determined by comparing with the gold standard inversion recovery spin ech...
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BACKGROUND The purpose of this work was to evaluate different magnetization preparation and readout sequences for modified Look-Locker inversion recovery (MOLLI) toward improved T1 mapping in the heart. Elements investigated include: catalyzation sequences to prepare the magnetization before readout, alternate k-space trajectories, a spoiled gradient recalled echo readout, and a 5b(3b)3b MOLLI ...
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OBJECT To develop and evaluate a 2D modified Look-Locker (MOLLI) for high-resolution T1 mapping in mice using a 3T MRI scanner. MATERIALS AND METHODS To allow high-resolution T1 mapping in mice at high heart rates a multi-shot ECG-triggered 2D MOLLI sequence was developed. In the proposed T1 mapping sequence the optimal number of sampling points and pause cardiac cycles following an initial a...
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عنوان ژورنال:
دوره 15 شماره
صفحات -
تاریخ انتشار 2013